Manchester United remain trapped in the relegation zone despite a wild 4-4 draw, while Manchester City's title hopes suffer another blow as Arsenal extend their lead.
Brighton claimed a historic 1-0 away win against Manchester City to close within two points of the Premier League leaders, while Chelsea compounded Manchester United's struggles with a 2-0 victory.
Liverpool defeated Chelsea in a dramatic penalty shoot-out to reach the League Cup quarter-finals, while Manchester City also survived on spot-kicks against Brighton.
Liverpool manager Andoni Iraola praised Alexander Isak for hitting top form, noting that the Sweden striker "feels the trust of everyone" ahead of their League Cup clash against Chelsea.
Andoni Iraola praised Alexander Isak's lethal form after the forward netted in Liverpool's 2-0 victory over Brighton, sealing Iraola's first Premier League win at Anfield.